cannabis indica

2-Araquidonoilglicerol (2-AG)

termo de indexação original: 2-Arachidonoyl Glycerol (2-AG)

O que é 2-Araquidonoilglicerol (2-AG)

O 2-araquidonoilglicerol, ou 2-AG, é o endocanabinoide mais abundante no cérebro — presente em concentrações muito maiores que a anandamida. Foi identificado em 1995, três anos depois dela, por grupos no Japão e em Israel.

Diferente da anandamida, o 2-AG é agonista total de CB1 e CB2: ativa os receptores com eficácia máxima. É sintetizado sob demanda pela enzima DAGL e degradado principalmente pela MAGL.

Seu papel mais conhecido é a sinalização retrógrada: o neurônio que recebe o sinal produz 2-AG e o envia de volta ao neurônio que enviou, reduzindo a liberação seguinte de neurotransmissor. É um mecanismo de freio — e uma das razões pelas quais o sistema endocanabinoide é descrito como regulador, e não como estimulante ou depressor.

No acervo

O acervo do Cannabis Indica reúne 498 estudos científicos que tocam o composto 2-Araquidonoilglicerol (2-AG), publicados entre 1996 e 2024. Pela leitura automatizada, 383 (77%) foram classificados como favoráveis, 86 (17%) como inconclusivos e 29 (6%) como desfavoráveis — uma leitura de máquina, feita para navegar, não para concluir. O desenho mais frequente é metanálise (236 estudos), seguido de estudo em animais (122). As condições mais associadas são Inflamação, Dor e Ansiedade.

Estudos indexados
498
Período coberto
1996–2024
Favoráveis
383 · 77%
Inconclusivos
86 · 17%
Desfavoráveis
29 · 6%
Termo original
2-Arachidonoyl Glycerol (2-AG)

O acervo em números

Tipo de estudo

Metanálise236
Estudo em Animais122
Estudo Laboratorial60
Ensaio Clínico52
Ensaio Clínico Duplo-Cego24
Metanálise Clínica4

Direção do resultado

Favorável383
Inconclusivo86
Desfavorável29

Por década

1990s2
2000s62
2010s212
2020s222

498 estudos

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Esta página mostra 304 dos 498 estudos indexados sobre o tema, dos mais recentes aos mais antigos. Abra o acervo com este filtro para percorrer todos, ou baixe a lista completa em JSON e CSV.

  1. 2024

    A systematic review of novel cannabinoids and their targets: Insights into the significance of structure in activity

    InconclusivoMetanáliseAnandamida (AEA)Endocanabinoide (não especificado)+3
  2. 2024

    Cannabinoid Analgesia in Postoperative Pain Management: From Molecular Mechanisms to Clinical Reality

    InconclusivoMetanáliseDorDor — AgudaAnandamida (AEA)Tetraidrocanabinol (THC)+7
  3. 2024

    Dietary linoleic acid lowering alone does not lower arachidonic acid or endocannabinoids among women with overweight and obesity: A randomized, controlled trial

  4. 2024

    Editorial: Insights on cannabinoid translational science and medicine: the endocannabinoidome as a target for clinical practice

    FavorávelMetanáliseAnandamida (AEA)Tetraidrocanabinol (THC)+9
  5. 2024

    Effects of Cannabidiol and Delta-9-Tetrahydrocannabinol on Plasma Endocannabinoid Levels in Healthy Volunteers: A Randomized Double-Blind Four-Arm Crossover Study

    InconclusivoEnsaio Clínico Duplo-CegoEfeitos Adversos da CannabisAnandamida (AEA)Tetraidrocanabinol (THC)+2
  6. 2024

    Endocannabinoid Hydrolase Inhibitors: Potential Novel Anxiolytic Drugs

    FavorávelMetanáliseAnsiedadeAnandamida (AEA)Endocanabinoide (não especificado)+4
  7. 2024

    Neurolipidomic insights into anxiety disorders: Uncovering lipid dynamics for potential therapeutic advances

  8. 2024

    Nutrient composition of different energy-restricted diets determines plasma endocannabinoid profiles and adipose tissue DAGL-α expression; a 12-week randomized controlled trial in subjects with abdominal obesity

  9. 2024

    The circulating and central endocannabinoid system in obesity and weight loss

    InconclusivoMetanáliseObesidadeAnandamida (AEA)Endocanabinoide (não especificado)
  10. 2023

    A systematic review of cannabidiol trials in neurodevelopmental disorders

  11. 2023

    Cannabidiol: Bridge between Antioxidant Effect, Cellular Protection, and Cognitive and Physical Performance

  12. 2023

    Cannabinoid Receptor 2 Blockade Prevents Anti-Depressive-like Effect of Cannabidiol Acid Methyl Ester in Female WKY Rats

    FavorávelEstudo em AnimaisDepressãoAnandamida (AEA)Canabinoide Sintético (não especificado)+4
  13. 2023

    Cannabinoid receptor type 1 (CB1R) inhibits hypothalamic leptin signaling via β-arrestin1 in complex with TC-PTP and STAT3

  14. 2023

    CBD supplementation reduces arterial blood pressure via modulation of the sympatho-chromaffin system: A substudy from the HYPER-H21-4 trial

    FavorávelEnsaio Clínico Duplo-CegoDoenças Cardiovasculares (DCV)Hipertensão ArterialAnandamida (AEA)
  15. 2023

    Circulating Endocannabinoid Levels as Potential Biomarkers for Mortality in Hemodialysis Patients

    FavorávelMetanáliseHemodiáliseAnandamida (AEA)
  16. 2023

    Co-ultramicronized palmitoylethanolamide/luteolin normalizes GABAB-ergic activity and cortical plasticity in long COVID-19 syndrome

    FavorávelEnsaio Clínico Duplo-CegoInflamaçãoDisfunção CognitivaEstresse OxidativoPalmitoiletanolamida (PEA)+1
  17. 2023

    Could cannabinoids provide a new hope for ovarian cancer patients?

  18. 2023

    Electroacupuncture Exerts Analgesic Effects by Restoring Hyperactivity via Cannabinoid Type 1 Receptors in the Anterior Cingulate Cortex in Chronic Inflammatory Pain

    FavorávelEnsaio ClínicoDorDor — CrônicaAnandamida (AEA)Acupuntura (MTC)
  19. 2023

    Endocannabinoid 2-Arachidonoylglycerol Synthesis and Metabolism at Neuronal Nuclear Matrix Fractions Derived from Adult Rat Brain Cortex

    FavorávelEstudo LaboratorialEstresse OxidativoAnandamida (AEA)Endocanabinoide (não especificado)+2
  20. 2023

    Endocannabinoid System and Exogenous Cannabinoids in Depression and Anxiety: A Review

  21. 2023

    Involvement of cannabinoid receptors and neuroinflammation in early sepsis: Implications for posttraumatic stress disorder

  22. 2023

    Molecular Insights into GPCR Mechanisms for Drugs of Abuse

  23. 2023

    Prenatal Exposure to Δ9-Tetrahydrocannabinol Affects Hippocampus-Related Cognitive Functions in the Adolescent Rat Offspring: Focus on Specific Markers of Neuroplasticity

  24. 2023

    Questioning the role of palmitoylethanolamide in psychosis: a systematic review of clinical and preclinical evidence

  25. 2023

    Regulatory role of the endocannabinoid system on glial cells toward cognitive function in Alzheimer's disease: A systematic review and meta-analysis of animal studies

  26. 2023

    Striatonigral direct pathway 2-arachidonoylglycerol contributes to ethanol effects on synaptic transmission and behavior

  27. 2022

    (Wh)olistic (E)ndocannabinoidome-Microbiome-Axis Modulation through (N)utrition (WHEN) to Curb Obesity and Related Disorders

  28. 2022

    2-Arachidonoyl glycerol suppresses gastric emptying via the cannabinoid receptor 1-cholecystokinin signaling pathway in mice

    InconclusivoEstudo em AnimaisDiarreiaConstipação
  29. 2022

    A Placebo-Controlled Trial of Cannabinoid Treatment for Disruptive Behavior in Children and Adolescents with Autism Spectrum Disorder: Effects on Sleep Parameters as Measured by the CSHQ

  30. 2022

    A randomized, controlled trial of ZYN002 cannabidiol transdermal gel in children and adolescents with fragile X syndrome (CONNECT-FX)

    FavorávelEnsaio Clínico Duplo-CegoAnsiedadeTranstornos de ComportamentoAutismoAnandamida (AEA)+2
  31. 2022

    A Systematic Review and Meta-Analysis on the Effects of Exercise on the Endocannabinoid System

  32. 2022

    Activation of cannabinoid receptors in breast cancer cells improves osteoblast viability in cancer-bone interaction model while reducing breast cancer cell survival and migration

  33. 2022

    Acute and long-term exercise differently modulate plasma levels of oxylipins, endocannabinoids, and their analogues in young sedentary adults: A sub-study and secondary analyses from the ACTIBATE randomized controlled-trial

  34. 2022

    Alterations of the endocannabinoid system and circulating and peripheral tissue levels of endocannabinoids in sarcopenic rats

  35. 2022

    Amygdalar CB2 cannabinoid receptor mediates fear extinction deficits promoted by orexin-A/hypocretin-1

  36. 2022

    Analysis of 2-Arachidonoylglycerol Levels in Polycystic Ovary Syndrome in the Context of Hormonal and Metabolic Alterations and Across the Classical Phenotypes

    InconclusivoMetanáliseSíndrome dos Ovários Policísticos
  37. 2022

    Cannabidiol as a personalized treatment for anxiety: clinical cases in Mexico

  38. 2022

    Cannabidiol in the context of substance use disorder treatment: A systematic review

  39. 2022

    Cannabidiol in Treatment of Autism Spectrum Disorder: A Case Study

  40. 2022

    Cannabinoid and vanilloid pathways mediate opposing forms of synaptic plasticity in corticotropin-releasing hormone neurons

    FavorávelEstudo LaboratorialEstresse OxidativoEndocanabinoide (não especificado)
  41. 2022

    Cannabinoids as anticancer drugs: current status of preclinical research

  42. 2022

    Cannabinoids as Glial Cell Modulators in Ischemic Stroke: Implications for Neuroprotection

  43. 2022

    Cannabinoids in rheumatology: Friend, foe or a bystander?

  44. 2022

    Cannabinoids-Perspectives for Individual Treatment in Selected Patients: Analysis of the Case Series

    FavorávelMetanáliseDorCâncerInflamaçãoAnandamida (AEA)Canabigerol (CBG)+13
  45. 2022

    Cannabis for Medical Use: Versatile Plant Rather Than a Single Drug

    FavorávelMetanáliseDorCâncerInflamaçãoAnandamida (AEA)Canabigerol (CBG)+18
  46. 2022

    Cannabis in Parkinson's Disease - the patient's perspective versus clinical trials: a systematic literature review

    DesfavorávelMetanálise ClínicaDorInflamaçãoAnsiedadeAnandamida (AEA)Endocanabinoide (não especificado)+5
  47. 2022

    Cannabis Use and the Endocannabinoid System: A Clinical Perspective

  48. 2022

    Cannabis-Based Products for the Treatment of Skin Inflammatory Diseases: A Timely Review

    FavorávelMetanáliseDorCâncerInflamaçãoAnandamida (AEA)Tetraidrocanabinol (THC)+28
  49. 2022

    Changes in the expression of endocannabinoid system components in an experimental model of chemotherapy-induced peripheral neuropathic pain: Evaluation of sex-related differences

  50. 2022

    Children and adolescents with ASD treated with CBD-rich cannabis exhibit significant improvements particularly in social symptoms: an open label study

  51. 2022

    Circulating endocannabinoid levels in pregnant women with gestational diabetes mellitus: a case-control study

    DesfavorávelMetanáliseDiabetesGestaçãoAnandamida (AEA)
  52. 2022

    Circulating endocannabinoids and genetic polymorphisms as predictors of posttraumatic stress disorder symptom severity: heterogeneity in a community-based cohort

    InconclusivoEnsaio ClínicoTEPTAnandamida (AEA)Endocanabinoide (não especificado)+1
  53. 2022

    Curcumin induces peripheral antinociception by opioidergic and cannabinoidergic mechanism: Pharmacological evidence

  54. 2022

    Cutaneous Squamous Cell Carcinoma and Lichen Simplex Chronicus Successfully Treated with Topical Cannabinoid Oil: A Case Report and Summary of Cannabinoids in Dermatology

  55. 2022

    Differential activation of G protein‐mediated signaling by synthetic cannabinoid receptor agonists

  56. 2022

    Differential expression of the neuronal CB1 cannabinoid receptor in the hippocampus of male Ts65Dn Down syndrome mouse model

    FavorávelEstudo em AnimaisSíndrome de DownAnandamida (AEA)Endocanabinoide (não especificado)+3
  57. 2022

    Does Cannabidiol Have a Benefit as a Supportive Care Drug in Cancer?

  58. 2022

    Dynamic Changes in the Endocannabinoid System during the Aging Process: Focus on the Middle-Age Crisis

    FavorávelEstudo em AnimaisLongevidadeAnandamida (AEA)Endocanabinoide (não especificado)
  59. 2022

    Early Blockade of CB1 Receptors Ameliorates Schizophrenia-like Alterations in the Neurodevelopmental MAM Model of Schizophrenia

  60. 2022

    Effect of the MAGL/FAAH Dual Inhibitor JZL-195 on Streptozotocin-Induced Alzheimer's Disease-like Sporadic Dementia in Mice with an Emphasis on Aβ, HSP-70, Neuroinflammation, and Oxidative Stress

  61. 2022

    Effect of Ultra-Micronized Palmitoylethanolamide and Luteolin on Olfaction and Memory in Patients with Long COVID: Results of a Longitudinal Study

    FavorávelEnsaio ClínicoInflamaçãoCOVID-19Anandamida (AEA)Palmitoiletanolamida (PEA)
  62. 2022

    Effects of non‐steroidal anti‐inflammatory drugs and other eicosanoid pathway modifiers on antiviral and allergic responses: EAACI task force on eicosanoids consensus report in times of COVID‐19

  63. 2022

    Effects of Rare Phytocannabinoids on the Endocannabinoid System of Human Keratinocytes

    FavorávelEstudo LaboratorialDoenças de PeleAnandamida (AEA)Endocanabinoide (não especificado)+7
  64. 2022

    Endocannabinoid Levels in Ulcerative Colitis Patients Correlate With Clinical Parameters and Are Affected by Cannabis Consumption

  65. 2022

    Endocannabinoid Modulation in Neurodegenerative Diseases: In Pursuit of Certainty

  66. 2022

    Endocannabinoid signaling in brain diseases: Emerging relevance of glial cells

  67. 2022

    Endocannabinoid signaling in glioma

  68. 2022

    Endocannabinoid System in Polycystic Kidney Disease

  69. 2022

    Enhancing endocannabinoid signalling in astrocytes promotes recovery from traumatic brain injury

  70. 2022

    Exercise-induced increases in Anandamide and BDNF during extinction consolidation contribute to reduced threat following reinstatement: Preliminary evidence from a randomized controlled trial

    FavorávelEnsaio ClínicoTEPTAnandamida (AEA)Exercício Físico
  71. 2022

    Exploring the endocannabinoidome in genetically obese (ob/ob) and diabetic (db/db) mice: Links with inflammation and gut microbiota

  72. 2022

    Expression and Functions of the CB 2 Receptor in Human Leukocytes

  73. 2022

    FABP5 deletion in nociceptors augments endocannabinoid signaling and suppresses TRPV1 sensitization and inflammatory pain

    FavorávelEstudo em AnimaisDorAnandamida (AEA)Hidrolase de Amidas de Ácidos Graxos (FAAH)+4
  74. 2022

    Fatty Acid Amide Hydrolase Deficiency Is Associated with Deleterious Cardiac Effects after Myocardial Ischemia and Reperfusion in Mice

  75. 2022

    Footshock-Induced Abstinence from Compulsive Methamphetamine Self-administration in Rat Model Is Accompanied by Increased Hippocampal Expression of Cannabinoid Receptors (CB1 and CB2)

  76. 2022

    Gene Expression Analysis of the Endocannabinoid System in Presymptomatic APP/PS1 Mice

  77. 2022

    Herbal Cannabis Use Is Not Associated with Changes in Levels of Endocannabinoids and Metabolic Profile Alterations among Older Adults

  78. 2022

    Immunomodulatory Role of CB2 Receptors in Emotional and Cognitive Disorders

  79. 2022

    In it together? The case for endocannabinoid–noradrenergic interactions in fear extinction

  80. 2022

    In vitro percutaneous absorption studies of cannabidiol using human skin: Exploring the effect of drug concentration, chemical enhancers, and essential oils

    FavorávelEstudo LaboratorialDorCâncerInflamaçãoAnandamida (AEA)Canabinoides Sintéticos AM-x+14
  81. 2022

    Influence of diet on acute endocannabinoidome mediator levels post exercise in active women, a crossover randomized study

  82. 2022

    Inhibiting Endocannabinoid Hydrolysis as Emerging Analgesic Strategy Targeting a Spectrum of Ion Channels Implicated in Migraine Pain

    FavorávelMetanáliseEnxaquecaAnandamida (AEA)Endocanabinoide (não especificado)+4
  83. 2022

    Involvement of the cannabinoid system in chronic inflammatory intestinal diseases: opportunities for new therapies

  84. 2022

    Modulation of Endocannabinoid System Components in Depression: Pre-Clinical and Clinical Evidence

  85. 2022

    Palmitoylethanolamide Reduces Proinflammatory Markers in Unvaccinated Adults Recently Diagnosed with COVID-19: A Randomized Controlled Trial

    FavorávelEnsaio Clínico Duplo-CegoCâncerInflamaçãoDoenças Cardiovasculares (DCV)Palmitoiletanolamida (PEA)+6
  86. 2022

    Phytocannabinoids and Cannabis-Based Products as Alternative Pharmacotherapy in Neurodegenerative Diseases: From Hypothesis to Clinical Practice

  87. 2022

    Practical Considerations for the Use of Cannabis in Cancer Pain Management—What a Medical Oncologist Should Know

  88. 2022

    Role of cannabis in inflammatory bowel diseases

  89. 2022

    Role of the endocannabinoid system in the pathophysiology of endometriosis and therapeutic implications

  90. 2022

    Sebaceous immunobiology - skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations

  91. 2022

    Sex differences in endocannabinoids during 3 years of Mediterranean diet intervention: Association with insulin resistance and weight loss in a population with metabolic syndrome

  92. 2022

    Synaptic changes induced by cannabinoid drugs and cannabis use disorder

  93. 2022

    Targeting the endocannabinoid system for the treatment of abdominal pain in irritable bowel syndrome

  94. 2022

    Targeting the Endocannabinoid System: From the Need for New Therapies to the Development of a Promising Strategy. What About Pancreatic Cancer?

  95. 2022

    Targeting the Endocannabinoidome in Pancreatic Cancer

  96. 2022

    The Autism–Psychosis Continuum Conundrum: Exploring the Role of the Endocannabinoid System

  97. 2022

    The effects of acute alcohol administration on circulating endocannabinoid levels in humans

  98. 2022

    The Endocannabinoid System and Physical Activity—A Robust Duo in the Novel Therapeutic Approach against Metabolic Disorders

  99. 2022

    The Endocannabinoid System as a Biomarker for Diagnostic and Therapeutic Applications in Depression and Anxiety

  100. 2022

    The endocannabinoids anandamide and 2-arachidonoylglycerol modulate the expression of angiogenic factors on HTR8/SVneo placental cells

    InconclusivoEstudo LaboratorialGestaçãoAnandamida (AEA)Endocanabinoide (não especificado)
  101. 2022

    The Role of Nutritional Status, Gastrointestinal Peptides, and Endocannabinoids in the Prognosis and Treatment of Children with Cancer

    InconclusivoMetanáliseDorCâncerObesidadeAnandamida (AEA)Tetraidrocanabinol (THC)+17
  102. 2022

    The role of the cannabinoid system in fear memory and extinction in male and female mice

    InconclusivoEstudo em AnimaisTEPTAnandamida (AEA)Canabinoide Sintético (não especificado)+4
  103. 2022

    Therapeutic Potential of Cannabinoids on Tumor Microenvironment: A Molecular Switch in Neoplasia Transformation

  104. 2022

    Tonic endocannabinoid signaling supports sleep through development in both sexes

  105. 2022

    Translation of animal endocannabinoid models of PTSD mechanisms to humans: Where to next?

  106. 2022

    Why Do Marijuana and Synthetic Cannabimimetics Induce Acute Myocardial Infarction in Healthy Young People?

  107. 2021

    A Cannabinoid 2-Selective Agonist Inhibits Allogeneic Skin Graft Rejection In Vivo

  108. 2021

    A Role for Peripheral Anandamide and 2-Arachidonoylglycerol in Short-Term Food Intake and Orexigenic Hypothalamic Responses in a Species with Continuous Nutrient Delivery

  109. 2021

    Alterations of the endocannabinoid system and its therapeutic potential in autism spectrum disorder

    FavorávelEstudo em AnimaisAutismoMonoacilglicerol Lipase (MAGL)Outros Compostos Relacionados
  110. 2021

    An Evaluation of Understudied Phytocannabinoids and Their Effects in Two Neuronal Models

  111. 2021

    Anti-aversive effect of 2-arachidonoylglycerol in the dorsolateral periaqueductal gray of male rats in contextual fear conditioning and Vogel tests

    FavorávelEstudo em AnimaisAnsiedadeTranstornos de ComportamentoTEPT
  112. 2021

    Anti-Inflammatory and Pro-Autophagy Effects of the Cannabinoid Receptor CB2R: Possibility of Modulation in Type 1 Diabetes

  113. 2021

    Anticancer Potential of Small-Molecule Inhibitors of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase

  114. 2021

    Brain imaging of cannabinoid type I (CB1 ) receptors in women with cannabis use disorder and male and female healthy controls

  115. 2021

    Cannabidiol and Neurodevelopmental Disorders in Children

  116. 2021

    Cannabigerol and cannabichromene in Cannabis sativa L.

    FavorávelMetanáliseCâncerInflamaçãoAnsiedadeAnandamida (AEA)Canabigerol (CBG)+12
  117. 2021

    Cannabinoid control of hippocampal functions: the where matters

  118. 2021

    Cannabinoids as Key Regulators of Inflammasome Signaling: A Current Perspective

  119. 2021

    Cannabinoids Drugs and Oral Health-From Recreational Side-Effects to Medicinal Purposes: A Systematic Review

  120. 2021

    Cannabinoids for skin diseases and hair regrowth

    InconclusivoMetanáliseQueda de CabeloCrescimento Anormal de PelosAnandamida (AEA)
  121. 2021

    Cannabinoids modulate food preference and consumption in Drosophila melanogaster

  122. 2021

    Cannabinoids—A New Perspective in Adjuvant Therapy for Pulmonary Hypertension

  123. 2021

    Cannabis and Autoimmunity: Possible Mechanisms of Action

  124. 2021

    Cannabis and Inflammation in HIV: A Review of Human and Animal Studies

  125. 2021

    Cannabis sativa: Interdisciplinary Strategies and Avenues for Medical and Commercial Progression Outside of CBD and THC

    FavorávelMetanáliseAnandamida (AEA)Hidrolase de Amidas de Ácidos Graxos (FAAH)+17
  126. 2021

    Changes in Hepatic Phospholipid Metabolism in Rats under UV Irradiation and Topically Treated with Cannabidiol

  127. 2021

    Circulating endocannabinoids and prospective risk for depression in trauma-injury survivors

  128. 2021

    Circulating Endocannabinoids as Diagnostic Markers of Canine Chronic Enteropathies: A Pilot Study

    InconclusivoEstudo em AnimaisAplicações VeterináriasAnandamida (AEA)
  129. 2021

    Circulating fatty acids and endocannabinoidome-related mediator profiles associated to human longevity

    FavorávelMetanáliseLongevidadeAnandamida (AEA)Palmitoiletanolamida (PEA)+2
  130. 2021

    Comorbid anxiety-like behavior in a rat model of colitis is mediated by an upregulation of corticolimbic fatty acid amide hydrolase

  131. 2021

    Early life stress and development of the endocannabinoid system: A bidirectional process in programming future coping

    InconclusivoMetanáliseGestaçãoAnandamida (AEA)
  132. 2021

    Endocannabinoid markers in autism spectrum disorder: A scoping review of human studies

    InconclusivoMetanálise ClínicaAutismoAnandamida (AEA)
  133. 2021

    Endocannabinoid Metabolism and Traumatic Brain Injury

  134. 2021

    Endocannabinoid Modulation Using Monoacylglycerol Lipase Inhibition in Tourette Syndrome: A Phase 1 Randomized, Placebo-Controlled Study

  135. 2021

    Endocannabinoid System as a Promising Therapeutic Target in Inflammatory Bowel Disease - A Systematic Review

  136. 2021

    Endocannabinoid-mediated synaptic plasticity and substance use disorders

  137. 2021

    Endocannabinoids and Heart Rate Variability Alterations after Exposure to Prolonged Intensive Physical Exercise of the Hellenic Navy SEALs

    FavorávelEnsaio ClínicoEstresse OxidativoAnandamida (AEA)Palmitoiletanolamida (PEA)+2
  138. 2021

    Endocannabinoids Attenuate the Virulence of Certain Enteropathogenic Bacteria

  139. 2021

    Endocannabinoids increase human adipose stem cell differentiation and growth factor secretion in vitro

    FavorávelEstudo LaboratorialAnandamida (AEA)
  140. 2021

    Exercise-induced euphoria and anxiolysis do not depend on endogenous opioids in humans

    FavorávelMetanáliseAnsiedadeAnandamida (AEA)
  141. 2021

    Experimental therapies in Irritable Bowel Syndrome

  142. 2021

    From the Clinic to the Laboratory, and Back Again: Investigations on Cannabinoids and Endocannabinoid System Modulators for Treating Schizophrenia

  143. 2021

    Genetic Variants of Fatty Acid Amide Hydrolase Modulate Acute Inflammatory Responses to Colitis in Adult Male Mice

  144. 2021

    Gut barrier and microbiota changes with glycine and branched-chain amino acid supplementation in chronic haemodialysis patients

    DesfavorávelEnsaio Clínico Duplo-CegoInflamaçãoInsuficiência RenalAnandamida (AEA)Endocanabinoide (não especificado)+3
  145. 2021

    Hair endocannabinoid concentrations in individuals with acute and weight-recovered anorexia nervosa

  146. 2021

    High levels of eicosanoids and docosanoids in the lungs of intubated COVID-19 patients

  147. 2021

    Human laryngeal squamous cell carcinoma cell line release of endogenous anandamide and 2-arachidonoylglycerol, and their antiproliferative effect via exogenous supplementation: an in vitro study

    FavorávelEstudo LaboratorialCâncerCâncer — BocaAnandamida (AEA)
  148. 2021

    Inverse correlation between plasma 2-arachidonoylglycerol levels and subjective severity of depression

    FavorávelMetanáliseDepressão
  149. 2021

    Lifestyle Interventions Improving Cannabinoid Tone During COVID-19 Lockdowns May Enhance Compliance With Preventive Regulations and Decrease Psychophysical Health Complications

  150. 2021

    Linking the Endocannabinoidome with Specific Metabolic Parameters in an Overweight and Insulin-Resistant Population: From Multivariate Exploratory Analysis to Univariate Analysis and Construction of Predictive Models

  151. 2021

    Mediterranean diet consumption affects the endocannabinoid system in overweight and obese subjects: possible links with gut microbiome, insulin resistance and inflammation

    FavorávelEnsaio ClínicoInflamaçãoObesidadeDiabetesAnandamida (AEA)Microbioma+2
  152. 2021

    Metabolic Consequences of Gestational Cannabinoid Exposure

  153. 2021

    Modulatory effect of 2-arachidonoylglycerol on voltage-gated sodium currents in rat caudate nucleus neurons with kainic acid-induced injury

    FavorávelEstudo em AnimaisExcitotoxicidade
  154. 2021

    Monoacylglycerol Lipase Inhibition in Tourette Syndrome: A 12-Week, Randomized, Controlled Study

    DesfavorávelEnsaio Clínico Duplo-CegoTDA e TDAHTiques e Síndrome de TouretteTOCAnandamida (AEA)Tetraidrocanabinol (THC)+1
  155. 2021

    Natural and Synthetic Cannabinoids: Pharmacology, Uses, Adverse Drug Events, and Drug Interactions

  156. 2021

    Neurobiological Processes Induced by Aerobic Exercise through the Endocannabinoidome

    FavorávelMetanáliseInflamaçãoAnsiedadeDepressãoAnandamida (AEA)+2
  157. 2021

    New Insights in the Involvement of the Endocannabinoid System and Natural Cannabinoids in Nicotine Dependence

  158. 2021

    Pharmacology, Clinical Effects, and Therapeutic Potential of Cannabinoids for Gastrointestinal and Liver Diseases

  159. 2021

    Phytocannabinoids—A Green Approach toward Non-Alcoholic Fatty Liver Disease Treatment

  160. 2021

    Plasmatic endocannabinoids are decreased in subjects with ultra-high risk of psychosis

    FavorávelMetanálisePsicoseEsquizofreniaAnandamida (AEA)
  161. 2021

    Polypharmacological Approaches for CNS Diseases: Focus on Endocannabinoid Degradation Inhibition

  162. 2021

    Protective role of endocannabinoid signaling in an animal model of haloperidol-induced tardive dyskinesia

  163. 2021

    Psychological and endocannabinoid responses to aerobic exercise in substance use disorder patients

  164. 2021

    Role of Cannabidiol in the Therapeutic Intervention for Substance Use Disorders

  165. 2021

    Synthetic Cannabinoids and Cathinones Cardiotoxicity: Facts and Perspectives

  166. 2021

    Targeting 2-arachidonoylglycerol signalling in the neurobiology and treatment of depression

    FavorávelMetanáliseDepressãoMonoacilglicerol Lipase (MAGL)
  167. 2021

    Targeting diacylglycerol lipase reduces alcohol consumption in preclinical models

  168. 2021

    Targeting the endocannabinoid system for management of HIV-associated neuropathic pain: A systematic review

  169. 2021

    Terpenoids Commonly Found in Cannabis sativa Do Not Modulate the Actions of Phytocannabinoids or Endocannabinoids on TRPA1 and TRPV1 Channels

    DesfavorávelEstudo LaboratorialAnandamida (AEA)Canabicromeno (CBC)+5
  170. 2021

    The cannabinoid system and microglia in health and disease

    FavorávelMetanáliseDorInflamaçãoAnsiedadeAnandamida (AEA)+8
  171. 2021

    The cannabinoid TRPA1 agonist cannabichromene inhibits nitric oxide production in macrophages and ameliorates murine colitis

  172. 2021

    The effects of FAAH inhibition on the neural basis of anxiety-related processing in healthy male subjects: a randomized clinical trial

    FavorávelEnsaio Clínico Duplo-CegoAnsiedadeTEPTAnandamida (AEA)Hidrolase de Amidas de Ácidos Graxos (FAAH)
  173. 2021

    The endocannabinoid 2-arachidonoylglycerol and dual ABHD6/MAGL enzyme inhibitors display neuroprotective and anti-inflammatory actions in the in vivo retinal model of AMPA excitotoxicity

    FavorávelEstudo em AnimaisInflamaçãoDoenças da Retina
  174. 2021

    The endocannabinoid 2-arachidonoylglycerol inhibits endothelial function and repair

    DesfavorávelEstudo em AnimaisDoenças Cardiovasculares (DCV)Aterosclerose
  175. 2021

    The endocannabinoid system - current implications for drug development

  176. 2021

    The Endocannabinoid System as Modulator of Exercise Benefits in Mental Health

  177. 2021

    The Endocannabinoid System: A Bridge between Alzheimer's Disease and Gut Microbiota

  178. 2021

    The influence of FAAH genetic variation on physiological, cognitive, and neural signatures of fear acquisition and extinction learning in women with PTSD

    FavorávelEnsaio ClínicoTEPTAnandamida (AEA)Hidrolase de Amidas de Ácidos Graxos (FAAH)+1
  179. 2021

    The Monoacylglycerol Lipase Inhibitor JZL184 Inhibits Lung Cancer Cell Invasion and Metastasis via the CB 1 Cannabinoid Receptor

    FavorávelEstudo em AnimaisCâncerCâncer — PulmãoMonoacilglicerol Lipase (MAGL)
  180. 2021

    The role of endocannabinoid pathway in the neuropathology of Alzheimer's disease: Can the inhibitors of MAGL and FAAH prove to be potential therapeutic targets against the cognitive impairment associated with Alzheimer's disease?

  181. 2021

    The role of endocannabinoids in pregnancy

  182. 2020

    A new role for anandamide: defective link between the systemic and skin endocannabinoid systems in hypertrophic human wound healing

  183. 2020

    Altered circulating endocannabinoids in anorexia nervosa during acute and weight-restored phases: A pilot study

    InconclusivoMetanáliseAnorexia (perda de apetite)Anorexia NervosaAnandamida (AEA)
  184. 2020

    Altered gut microbiota and endocannabinoid system tone in vitamin D deficiency-mediated chronic pain

  185. 2020

    An inverse agonist of estrogen-related receptor γ regulates 2-arachidonoylglycerol synthesis by modulating diacylglycerol lipase expression in alcohol-intoxicated mice

    FavorávelEstudo em AnimaisDoença Hepática AlcoólicaOutros Compostos Relacionados
  186. 2020

    An optimized spectrophotometric assay reveals increased activity of enzymes involved in 2-arachidonoyl glycerol turnover in the cerebral cortex of a rat model of Alzheimer's disease

    FavorávelEstudo em AnimaisDoença de AlzheimerMonoacilglicerol Lipase (MAGL)
  187. 2020

    Anandamide Metabolites Protect against Seizures through the TRP Channel Water Witch in Drosophila melanogaster

    FavorávelEstudo em AnimaisEpilepsiaAnandamida (AEA)
  188. 2020

    Assessment of boron-containing compounds and oleoylethanolamide supplementation on the recovery trend in patients with COVID-19: A structured summary of a study protocol for a randomized controlled trial

  189. 2020

    Associating Emergency Medical Services personnel's workload, trauma exposure, and health with the cortisol, endocannabinoid, and N-acylethanolamine concentrations in their hair

    DesfavorávelEnsaio ClínicoDorAnsiedadeDepressãoAnandamida (AEA)Palmitoiletanolamida (PEA)+4
  190. 2020

    Beyond THC and Endocannabinoids

  191. 2020

    Can Physical Activity Support the Endocannabinoid System in the Preventive and Therapeutic Approach to Neurological Disorders?

  192. 2020

    Cannabidiol Oil-Associated Microscopic Colitis

    DesfavorávelMetanáliseDorInflamaçãoEfeitos Adversos da CannabisAnandamida (AEA)+3
  193. 2020

    Cannabinoid-profiled agents improve cell survival via reduction of oxidative stress and inflammation, and Nrf2 activation in a toxic model combining hyperglycemia+Aβ 1-42 peptide in rat hippocampal neurons

    FavorávelEstudo LaboratorialDoença de AlzheimerAnandamida (AEA)Canabinoides Sintéticos WIN-x+2
  194. 2020

    Cannabinoids and Cannabinoid Receptors: The Story so Far

    InconclusivoMetanáliseAnandamida (AEA)Canabigerol (CBG)+5
  195. 2020

    Cannabinoids and Chronic Liver Diseases

  196. 2020

    Cannabinoids, Endocannabinoids and Sleep

  197. 2020

    Chronic Cannabidiol Administration Fails to Diminish Blood Pressure in Rats With Primary and Secondary Hypertension Despite Its Effects on Cardiac and Plasma Endocannabinoid System, Oxidative Stress and Lipid Metabolism

  198. 2020

    Diacylglycerol lipase alpha in astrocytes is involved in maternal care and affective behaviors

    InconclusivoEstudo em AnimaisDepressãoGestaçãoMonoacilglicerol Lipase (MAGL)
  199. 2020

    Dietary fatty acid intake and gut microbiota determine circulating endocannabinoidome signaling beyond the effect of body fat

  200. 2020

    Effects of the monoacylglycerol lipase inhibitor JZL184 on chickens infected with avian pathogenic Escherichia coli O78: A preliminary pharmacokinetic and infection study

  201. 2020

    Endocannabinoid modulation of dopamine release during reward seeking, interval timing, and avoidance

  202. 2020

    Endocannabinoid System and Cannabinoid 1 Receptors in Patients With Pharmacoresistant Temporal Lobe Epilepsy and Comorbid Mood Disorders

    FavorávelMetanáliseEpilepsiaAnandamida (AEA)
  203. 2020

    Endocannabinoid system and cardiometabolic risk factors: A comprehensive systematic review insight into the mechanistic effects of omega-3 fatty acids

  204. 2020

    Endocannabinoids and Stroke Prevention: Review of Clinical Studies

    FavorávelMetanálise ClínicaAVCAnandamida (AEA)
  205. 2020

    Endocannabinoids Inhibit the Induction of Virulence in Enteric Pathogens

  206. 2020

    Gene Expression Analysis of Astrocyte and Microglia Endocannabinoid Signaling during Autoimmune Demyelination

    FavorávelEstudo LaboratorialEsclerose Múltipla
  207. 2020

    GPR119 Is a Potent Regulator of Human Sebocyte Biology

  208. 2020

    Imbalance of Endocannabinoid/Lysophosphatidylinositol Receptors Marks the Severity of Alzheimer’s Disease in a Preclinical Model: A Therapeutic Opportunity

  209. 2020

    Impact of a weight loss and fitness intervention on exercise-associated plasma oxylipin patterns in obese, insulin-resistant, sedentary women

  210. 2020

    Increased Anandamide and Decreased Pain and Depression after Exercise in Fibromyalgia

    FavorávelEnsaio ClínicoDorDor — CrônicaDepressãoAnandamida (AEA)Exercício Físico+1
  211. 2020

    Inner Engineering Practices and Advanced 4-day Isha Yoga Retreat Are Associated with Cannabimimetic Effects with Increased Endocannabinoids and Short-Term and Sustained Improvement in Mental Health: A Prospective Observational Study of Meditators

    FavorávelMetanáliseDorAnsiedadeDepressãoAnandamida (AEA)Exercício Físico+3
  212. 2020

    Mgll Knockout Mouse Resistance to Diet-Induced Dysmetabolism Is Associated with Altered Gut Microbiota

  213. 2020

    Molecular Targets of Cannabidiol in Experimental Models of Neurological Disease

  214. 2020

    Neural Stem Cells and Cannabinoids in the Spotlight as Potential Therapy for Epilepsy

  215. 2020

    Role of endocannabinoid signaling in a septohabenular pathway in the regulation of anxiety- and depressive-like behavior

    FavorávelEstudo em AnimaisAnsiedadeDepressãoAnandamida (AEA)Monoacilglicerol Lipase (MAGL)
  216. 2020

    Role of the endocannabinoid system in the regulation of the skeletal muscle response to exercise

  217. 2020

    Terpenoids From Cannabis Do Not Mediate an Entourage Effect by Acting at Cannabinoid Receptors

    DesfavorávelEstudo Laboratorial
  218. 2020

    THC Regulates Tearing via Cannabinoid CB1 Receptors

    InconclusivoEstudo em AnimaisDorDor — OcularUveíteAnandamida (AEA)Canabinoides Sintéticos CP-x
  219. 2020

    The Endocannabinoid System Alleviates Pain in a Murine Model of Cancer-Induced Bone Pain

    FavorávelEstudo em AnimaisDorCâncerCâncer — MamaMonoacilglicerol Lipase (MAGL)+2
  220. 2020

    The Endocannabinoid System May Modulate Sleep Disorders in Aging

  221. 2020

    Whey protein supplementation reducing fasting levels of anandamide and 2-AG without weight loss in pre-menopausal women with obesity on a weight-loss diet

    FavorávelEnsaio Clínico Duplo-CegoCâncerInflamaçãoDoenças Cardiovasculares (DCV)Anandamida (AEA)+8
  222. 2020

    Δ 9 -Tetrahydrocannabinol promotes oligodendrocyte development and CNS myelination in vivo

    FavorávelEstudo em AnimaisEsclerose Múltipla
  223. 2019

    2-Arachidonoylglycerol Mobilizes Myeloid Cells and Worsens Heart Function After Acute Myocardial Infarction

    InconclusivoEstudo em AnimaisDoenças Cardiovasculares (DCV)InfartoMonoacilglicerol Lipase (MAGL)
  224. 2019

    Cannabinoid Regulation of Fear and Anxiety: an Update

  225. 2019

    Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System

  226. 2019

    Cannabinoids and bone regeneration

    FavorávelMetanáliseFraturas ÓsseasAnandamida (AEA)Canabinoides Sintéticos AM-x+3
  227. 2019

    Cannabinoids and Dementia: A Review of Clinical and Preclinical Data

  228. 2019

    Countering the Modern Metabolic Disease Rampage With Ancestral Endocannabinoid System Alignment

  229. 2019

    Elevated Levels of Arachidonic Acid-Derived Lipids Including Prostaglandins and Endocannabinoids Are Present Throughout ABHD12 Knockout Brains: Novel Insights Into the Neurodegenerative Phenotype

    InconclusivoEstudo em AnimaisDoenças NeurodegenerativasCondições GeriátricasCatarata
  230. 2019

    Endocannabinoid System and the Kidneys: From Renal Physiology to Injury and Disease

  231. 2019

    Endocannabinoid System Components as Potential Biomarkers in Psychiatry

  232. 2019

    Endocannabinoid System in Hepatic Glucose Metabolism, Fatty Liver Disease, and Cirrhosis

  233. 2019

    Endocannabinoid system in systemic lupus erythematosus: First evidence for a deranged 2-arachidonoylglycerol metabolism

    FavorávelEstudo LaboratorialLúpusOutros Compostos Relacionados
  234. 2019

    Food database of N-acyl-phosphatidylethanolamines, N-acylethanolamines and endocannabinoids and daily intake from a Western, a Mediterranean and a vegetarian diet

    InconclusivoEstudo LaboratorialAnandamida (AEA)Outros Compostos Relacionados+1
  235. 2019

    Future Aspects for Cannabinoids in Breast Cancer Therapy

  236. 2019

    Hypothalamic endocannabinoid signalling modulates aversive responses related to panic attacks.

    FavorávelEstudo em AnimaisAnsiedadeAnandamida (AEA)Canabinoide Sintético (não especificado)+5
  237. 2019

    Impaired brain endocannabinoid tone in the activity-based model of anorexia nervosa

    InconclusivoEstudo em AnimaisAnorexia NervosaAnandamida (AEA)
  238. 2019

    Interferon γ Treatment Increases Endocannabinoid and Related N-acylethanolamine Levels in T84 Human Colon Carcinoma Cells

    InconclusivoEstudo LaboratorialCâncerCâncer — CólonAnandamida (AEA)
  239. 2019

    Lifestyle and Metabolic Syndrome: Contribution of the Endocannabinoidome

  240. 2019

    Lower circulating endocannabinoid levels in children with autism spectrum disorder

  241. 2019

    Members of the endocannabinoid system are distinctly regulated in inflammatory bowel disease and colorectal cancer

  242. 2019

    Monoacylglycerol lipase inhibition as potential treatment for interstitial cystitis

    FavorávelEstudo em AnimaisCistite
  243. 2019

    Opposite roles of cannabinoid receptor 1 and 2 in hepatocarcinogenesis

  244. 2019

    Palmitoylethanolamide counteracts substance P-induced mast cell activation in vitro by stimulating diacylglycerol lipase activity

  245. 2019

    Paradoxical Effects of JZL184, an Inhibitor of Monoacylglycerol Lipase, on Bone Remodelling in Healthy and Cancer-Bearing Mice

  246. 2019

    Plants come to mind: phytocannabinoids, endocannabinoids and the control of seizures

  247. 2019

    Potential Mechanisms Influencing the Inverse Relationship Between Cannabis and Nonalcoholic Fatty Liver Disease: A Commentary

    FavorávelMetanáliseEsteatose HepáticaAnandamida (AEA)Tetraidrocanabinol (THC)+1
  248. 2019

    Repetitive high-frequency transcranial magnetic stimulation reverses depressive-like behaviors and protein expression at hippocampal synapses in chronic unpredictable stress-treated rats by enhancing endocannabinoid signaling

    FavorávelEstudo em AnimaisDepressãoAnandamida (AEA)Endocanabinoide (não especificado)+3
  249. 2019

    Role of Cannabinoid Receptor Type 1 in Insulin Resistance and Its Biological Implications

  250. 2019

    Role of chronic cannabis use: Cyclic vomiting syndrome vs cannabinoid hyperemesis syndrome

  251. 2019

    Serum Endocannabinoid and Mood Changes after Exercise in Major Depressive Disorder

    FavorávelEnsaio ClínicoAnsiedadeDepressãoAnandamida (AEA)
  252. 2019

    Systematic review of the potential role of cannabinoids as antiproliferative agents for urological cancers

    InconclusivoMetanáliseCâncerCâncer — MamaCâncer — Cérebro+4
  253. 2019

    The association between endogenous opioid function and morphine responsiveness: a moderating role for endocannabinoids

  254. 2019

    The Endocannabinoid System as a Window Into Microglial Biology and Its Relationship to Autism

  255. 2019

    The Endocannabinoid System of Animals

  256. 2019

    Therapeutic Efficacy of Palmitoylethanolamide and Its New Formulations in Synergy with Different Antioxidant Molecules Present in Diets

  257. 2018

    2-AG limits Theiler's virus induced acute neuroinflammation by modulating microglia and promoting MDSCs.

    FavorávelEstudo em AnimaisEsclerose MúltiplaMonoacilglicerol Lipase (MAGL)
  258. 2018

    Anti-inflammatory Properties of Cannabidiol, a Nonpsychotropic Cannabinoid, in Experimental Allergic Contact Dermatitis.

  259. 2018

    Cannabinoid-induced Cell Death In Endometrial Cancer Cells: Involvement Of TRPV1 Receptors In Apoptosis

    FavorávelEstudo LaboratorialCâncerCâncer — ÚteroAnandamida (AEA)
  260. 2018

    Cannabinoids and Gastrointestinal Motility: Pharmacology, Clinical Effects, and Potential Therapeutics in Humans

  261. 2018

    Cannabinoids, the Heart of the Matter.

  262. 2018

    Cannabis and pediatric inflammatory bowel disease: change blossoms a mile high.

  263. 2018

    Cannabis sativa L. and Nonpsychoactive Cannabinoids: Their Chemistry and Role against Oxidative Stress, Inflammation, and Cancer

    FavorávelMetanáliseDorCâncerInflamaçãoAnandamida (AEA)THC Farmacêutico+5
  264. 2018

    Chronic Stress Induces Anxiety via an Amygdalar Intracellular Cascade that Impairs Endocannabinoid Signaling.

    FavorávelEstudo em AnimaisAnsiedadeAnandamida (AEA)Canabinoides Sintéticos AM-x+1
  265. 2018

    Controlled-Deactivation CB1 Receptor Ligands as a Novel Strategy to Lower Intraocular Pressure.

    FavorávelEstudo em AnimaisGlaucomaTetraidrocanabinol (THC)Canabinoides Sintéticos AM-x+1
  266. 2018

    Detrimental effects of 2-arachidonoylglycerol on whole blood platelet aggregation and on cerebral blood flow after a focal ischemic insult in rats

    InconclusivoEstudo em AnimaisAVCCanabinoide Sintético (não especificado)
  267. 2018

    Effect of Cannabidiol on Medial Temporal, Midbrain, and Striatal Dysfunction in People at Clinical High Risk of Psychosis: A Randomized Clinical Trial

    FavorávelEnsaio Clínico Duplo-CegoAnsiedadeDisfunção CognitivaPsicoseAnandamida (AEA)Palmitoiletanolamida (PEA)+1
  268. 2018

    Effects of a Weight Loss Program on Metabolic Syndrome, Eating Disorders and Psychological Outcomes: Mediation by Endocannabinoids?

  269. 2018

    Effects of repeated long‐term psychosocial stress and acute cannabinoid exposure on mouse corticostriatal circuitries: Implications for neuropsychiatric disorders.

    FavorávelEstudo em AnimaisAnandamida (AEA)Canabinoide Sintético (não especificado)+4
  270. 2018

    Emerging Role of (Endo)Cannabinoids in Migraine

  271. 2018

    Endocannabinoid and Opioid System Interactions in Exercise-Induced Hypoalgesia

    FavorávelEnsaio Clínico Duplo-CegoDorDor — AgudaAnandamida (AEA)Exercício Físico
  272. 2018

    Endocannabinoids affect innate immunity of Muller glia during HIV-1 Tat cytotoxicity.

    FavorávelEstudo LaboratorialUveíteAnandamida (AEA)Canabinoides Sintéticos AM-x+1
  273. 2018

    Endocannabinoids in Body Weight Control

  274. 2018

    Innovative Therapeutic Potential of Cannabinoid Receptors as Targets in Alzheimer's disease and Less Well-Known Diseases.

  275. 2018

    Mechanistic Potential and Therapeutic Implications of Cannabinoids in Nonalcoholic Fatty Liver Disease

  276. 2018

    Median nerve stimulation induces analgesia via orexin-initiated endocannabinoid disinhibition in the periaqueductal gray

    FavorávelEstudo em AnimaisDorDor — CrônicaMonoacilglicerol Lipase (MAGL)Acupuntura (MTC)
  277. 2018

    Neuroprotection by (Endo)Cannabinoids in Glaucoma and Retinal Neurodegenerative Diseases

  278. 2018

    Peripheral Endocannabinoids Associated With Energy Expenditure in Native Americans of Southwestern Heritage

  279. 2018

    Polyunsaturated fatty acids and endocannabinoids in health and disease

  280. 2018

    Potential of Endocannabinoids to Control Bladder Pain.

  281. 2018

    Prophylactic Palmitoylethanolamide Prolongs Survival and Decreases Detrimental Inflammation in Aged Mice With Bacterial Meningitis

  282. 2018

    Psychobiological Responses to Aerobic Exercise in Individuals With Posttraumatic Stress Disorder.

    FavorávelEnsaio ClínicoTEPTAnandamida (AEA)Outros Compostos Relacionados
  283. 2018

    Role of Cannabinoids in Obesity

    FavorávelMetanáliseObesidadeAnandamida (AEA)Canabinoides Sintéticos AM-x+2
  284. 2018

    Role of Endocannabinoids on Sweet Taste Perception, Food Preference, and Obesity-related Disorders

  285. 2018

    Role of the endocannabinoid system in neurological disorders.

    FavorávelMetanáliseAutismoAnandamida (AEA)Endocanabinoide (não especificado)+3
  286. 2018

    Salivary endocannabinoids and N-acylethanolamines upon mastication of a semisolid food: implications in fat taste, appetite and food liking

    InconclusivoEnsaio Clínico Duplo-CegoPerda de Apetite
  287. 2018

    The Endogenous Cannabinoid System: A Budding Source of Targets for Treating Inflammatory and Neuropathic Pain

  288. 2018

    The Relationship of Endocannabinoidome Lipid Mediators With Pain and Psychological Stress in Women With Fibromyalgia: A Case-Control Study

    FavorávelEnsaio Clínico Duplo-CegoDorInflamaçãoAnsiedadeAnandamida (AEA)Endocanabinoide (não especificado)+4
  289. 2018

    The Role of Cannabinoids in the Setting of Cirrhosis.

    FavorávelMetanáliseFibroseFibrose — Hepática (Cirrose)Anandamida (AEA)
  290. 2018

    Theoretical Explanation for Reduced Body Mass Index and Obesity Rates in Cannabis Users

  291. 2018

    Traditional Uses of Cannabinoids and New Perspectives in the Treatment of Multiple Sclerosis.

    FavorávelMetanáliseEsclerose MúltiplaAnandamida (AEA)Tetraidrocanabinol (THC)+9
  292. 2017

    2-Arachidonoylglycerol as a possible treatment for anorexia nervosa in animal model in mice

    FavorávelEstudo em AnimaisAnorexia (perda de apetite)Anorexia Nervosa
  293. 2017

    A Pulsed Electromagnetic Field Protects against Glutamate-Induced Excitotoxicity by Modulating the Endocannabinoid System in HT22 Cells

  294. 2017

    Cannabinoid Receptor-2 Ameliorates Inflammation in Murine Model of Crohn’s Disease

  295. 2017

    Cannabinoids and the kidney: effects in health and disease

  296. 2017

    Cannabinoids for treating inflammatory bowel diseases: where are we and where do we go?

  297. 2017

    Cannabinoids Regulate the Diameter of Pericyte-Containing Retinal Capillaries in Rats

    FavorávelEstudo em AnimaisDorDor — OcularAnandamida (AEA)Canabinoides Sintéticos AM-x+2
  298. 2017

    Changes in the Brain Endocannabinoid System in Rat Models of Depression

    InconclusivoEstudo em AnimaisDepressãoAnandamida (AEA)Hidrolase de Amidas de Ácidos Graxos (FAAH)+1
  299. 2017

    Circulating levels of endocannabinoids respond acutely to voluntary exercise, are altered in mice selectively bred for high voluntary wheel running, and differ between the sexes

    FavorávelEstudo em AnimaisAnandamida (AEA)
  300. 2017

    Consequence of dopamine D2 receptor blockade on the hyperphagic effect induced by cannabinoid CB1 and CB2 receptors in layers

    FavorávelEstudo em AnimaisPerda de Apetite
  301. 2016

    Reductions in circulating endocannabinoid 2-arachidonoylglycerol levels in healthy human subjects exposed to chronic stressors.

    FavorávelEnsaio ClínicoAnandamida (AEA)
  302. 2015

    Endocannabinoid signaling at the periphery: 50 years after THC

    InconclusivoMetanáliseAnandamida (AEA)Endocanabinoide (não especificado)
  303. 2011

    Involvement of the Endocannabinoid System in the Neurobehavioral Effects of Stress and Glucocorticoids.

    FavorávelMetanáliseAnandamida (AEA)
  304. 2010

    Repeated Homotypic Stress Elevates 2-Arachidonoylglycerol Levels and Enhances Short-Term Endocannabinoid Signaling at Inhibitory Synapses in Basolateral Amygdala

    FavorávelEstudo em Animais

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Perguntas frequentes

Quantos estudos sobre 2-araquidonoilglicerol (2-ag) estão indexados no acervo?
São 498 estudos, publicados entre 1996 e 2024. O acervo inteiro tem 7.640 registros.
Que tipos de estudo predominam?
Metanálise: 236 · Estudo em Animais: 122 · Estudo Laboratorial: 60 · Ensaio Clínico: 52 · Ensaio Clínico Duplo-Cego: 24 · Metanálise Clínica: 4. A classificação segue o desenho declarado na fonte.
O que significa a classificação de resultado?
É uma leitura automatizada da conclusão de cada estudo, em três direções — favorável, inconclusivo e desfavorável. Aqui são 383 favoráveis, 86 inconclusivos e 29 desfavoráveis. Serve para navegar o acervo, não para concluir nada clinicamente: a conclusão válida é a do artigo original.

Como citar esta página

ABNT

CANNABIS INDICA. 2-Araquidonoilglicerol (2-AG) — estudos científicos sobre cannabis. 2026. Disponível em: https://cannabisindica.com.br/canabinoide/2-araquidonoilglicerol-2-ag/. Acesso em: 13 set. 2026.

APA

Cannabis Indica. (2026). 2-Araquidonoilglicerol (2-AG) — estudos científicos sobre cannabis. https://cannabisindica.com.br/canabinoide/2-araquidonoilglicerol-2-ag/

Esta página é um índice de acesso. Ao usar um estudo como evidência, cite o artigo original — o link de cada registro leva à fonte.