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Estudos 2.301 a 2.400 de 7.640, ordenados do mais recente ao mais antigo — nesta página, publicações de 2021. Para buscar por termo ou combinar filtros, use o acervo com busca.

2021
Inhibition of Efflux Pumps by Monoterpene (α-pinene) and Impact on Staphylococcus aureus Resistance to Tetracycline and Erythromycin
FavorávelEstudo LaboratorialInfecções Bacterianas Infecção por Estafilococos
2021
Inhibition of Fatty Acid Amide Hydrolase (FAAH) During Adolescence and Exposure to Early Life Stress may Exacerbate Depression-like Behaviors in Male and Female Rats
FavorávelEstudo em AnimaisDepressão Hidrolase de Amidas de Ácidos Graxos (FAAH)
2021
Inhibition of sodium conductance by cannabigerol contributes to a reduction of dorsal root ganglion neuron excitability
FavorávelEstudo LaboratorialDor Dor — Aguda Canabigerol (CBG)
2021
Insulin Receptor Substrate 1 Is Involved in the Phycocyanin-Mediated Antineoplastic Function of Non-Small Cell Lung Cancer Cells
FavorávelEstudo LaboratorialCâncer Câncer — Pulmão Ficocianina
2021
Integrated cognitive-behavioral therapy for comorbid cannabis use and anxiety disorders: The impact of severity of cannabis use
FavorávelEnsaio ClínicoDependência — Cannabis Ansiedade
2021
Intelligence quotient decline following frequent or dependent cannabis use in youth: a systematic review and meta-analysis of longitudinal studies
DesfavorávelMetanáliseDependência Química Efeitos Adversos da Cannabis Dependência — Cannabis+1
2021
Interaction of cannabidiol with other antiseizure medications: A narrative review
FavorávelMetanáliseEpilepsia
2021
Interactions between lysophosphatidylinositol receptor GPR55 and sphingosine-1-phosphate receptor S1P5 in live cells
FavorávelEstudo LaboratorialCâncer Câncer — Cólon Endocanabinoide (não especificado)Lisofosfatidilinositol (LPI)
2021
Interim Results of the Survey Accompanying the Prescription of Cannabis-Based Medicines in Germany Regarding Dronabinol
FavorávelMetanáliseDor Dor — Crônica THC Farmacêutico
2021
International Association for the Study of Pain Presidential Task Force on Cannabis and Cannabinoid Analgesia: research agenda on the use of cannabinoids, cannabis, and cannabis-based medicines for pain management
FavorávelMetanáliseDor Dor — Crônica Dor — Aguda+6
2021
Intranasal temperature-sensitive hydrogels of cannabidiol inclusion complex for the treatment of post-traumatic stress disorder
FavorávelEstudo em AnimaisInflamação TEPT
2021
Intravenous Haloperidol Versus Ondansetron for Cannabis Hyperemesis Syndrome (HaVOC): A Randomized, Controlled Trial
FavorávelEnsaio Clínico Duplo-CegoDor Dependência Química Efeitos Adversos da Cannabis+3
2021
Inverse correlation between plasma 2-arachidonoylglycerol levels and subjective severity of depression
FavorávelMetanáliseDepressão 2-Araquidonoilglicerol (2-AG)
2021
Investigating interventions that lead to the highest treatment retention for emerging adults with substance use disorder: A systematic review
FavorávelMetanáliseDependência Química Dependência — Cannabis Dependência — Opioides+1
2021
Investigation of antinociceptive, antipyretic, antiasthmatic, and spasmolytic activities of Brazilian Cannabis sativa L. roots in rodents
FavorávelEstudo em AnimaisDor Inflamação Dor — Aguda+1
2021
Investigation of in vitro odonto/osteogenic capacity of cannabidiol on human dental pulp cell
FavorávelEstudo LaboratorialDor Dor — Aguda Cáries+1
2021
Involvement of Hippocampal D1-Like Dopamine Receptors in the Inhibitory Effect of Cannabidiol on Acquisition and Expression of Methamphetamine-Induced Conditioned Place Preference
FavorávelEstudo em AnimaisDependência Química Dependência — Cocaína Dependência — Estimulantes
2021
Involvement of the endocannabinoid system in the inhibition of Sindbis virus replication: a preliminary study
InconclusivoEstudo LaboratorialDoenças Priônicas Canabinoide Sintético (não especificado)Canabinoides Sintéticos AM-x
2021
Is marijuana really a gateway drug? A nationally representative test of the marijuana gateway hypothesis using a propensity score matching design
InconclusivoMetanáliseDependência — Opioides Dependência — Álcool Dependência — Cocaína+1
2021
Is there a rational basis for cannabinoids research and development in ocular pain therapy? A systematic review of preclinical evidence
InconclusivoMetanáliseDor Inflamação Dor — Ocular Endocanabinoide (não especificado)Canabinoides Sintéticos HU-x+1
2021
Isolation, Synthesis And Structure Determination Of Cannabidiol Derivatives And Their Cytotoxic Activities
FavorávelEstudo LaboratorialCâncer
2021
Juvenile cannabidiol chronic treatments produce robust changes in metabolic markers in adult male Wistar rats
InconclusivoEstudo em AnimaisDoenças Cardiovasculares (DCV)Diabetes Síndrome Metabólica+1
2021
Kaposi-Juliusberg Varicelliform Eruption complicating Darier disease: May cannabinoid abuse be an underestimated risk factor?
DesfavorávelMetanáliseDependência Química Dependência — Cannabis Cicatrização+2
2021
Knowledge and attitudes of Italian medical oncologists and palliative care physicians toward medical use of cannabis in cancer care: a national survey
FavorávelMetanáliseDor Câncer Insônia e Distúrbios do Sono+3
2021
Knowledge, Perception, and Use of Cannabis Therapy in Patients with Inflammatory Bowel Disease
FavorávelMetanáliseDII — Doença Inflamatória Intestinal
2021
Lack of Association Between Recent Cannabis Use and Advanced Liver Fibrosis Among HIV-positive Heavy Drinkers
InconclusivoMetanáliseDependência Química Inflamação Dependência — Álcool+3
2021
Latency to cannabis dependence mediates the relationship between age at cannabis use initiation and cannabis use outcomes during treatment in men but not women
DesfavorávelMetanáliseDependência Química Efeitos Adversos da Cannabis Dependência — Cannabis
2021
Lavender and coriander essential oils and their main component linalool exert a protective effect against amyloid-β neurotoxicity
FavorávelEstudo LaboratorialDoença de Alzheimer Demência Medicina Mente-Corpo
2021
Legalization of cannabis use in Canada: Impacts on the cannabis use profiles of youth seeking services for substance use
InconclusivoMetanáliseDependência Química Efeitos Adversos da Cannabis Dependência — Cannabis
2021
Less COVID-19 deaths in southern and insular Italy explained by forest bathing, Mediterranean environment, and antiviral plant volatile organic compounds
FavorávelMetanáliseCOVID-19
2021
Lethal case of myocardial ischemia following overdose of the synthetic cannabinoid ADB-FUBINACA
DesfavorávelMetanáliseInflamação Efeitos Adversos da Cannabis Doenças Cardiovasculares (DCV)Canabinoide Sintético (não especificado)+13
2021
Letter to the Editor: Ordering the Chaos in Cannabinoid-Related Research: Is it Time for a Task Force on Taxonomy?
FavorávelMetanáliseEndocanabinoide (não especificado)
2021
Lifestyle Interventions Improving Cannabinoid Tone During COVID-19 Lockdowns May Enhance Compliance With Preventive Regulations and Decrease Psychophysical Health Complications
FavorávelMetanáliseAnsiedade Transtornos de Comportamento COVID-19 Anandamida (AEA)Endocanabinoide (não especificado)+4
2021
Lifetime Cannabis Use Disorder Is Not Associated With Lifetime Impulsive Behavior and Severe Violence in Patients With Schizophrenia Spectrum Disorders From a High-Security Hospital
InconclusivoMetanáliseDependência — Cannabis Esquizofrenia Violência Doméstica+1
2021
Limonene has anti-anxiety activity via adenosine A2A receptor-mediated regulation of dopaminergic and GABAergic neuronal function in the striatum
FavorávelEstudo em AnimaisAnsiedade
2021
Limonene through Attenuation of Neuroinflammation and Nitrite Level Exerts Antidepressant-Like Effect on Mouse Model of Maternal Separation Stress
FavorávelEstudo em AnimaisInflamação Depressão
2021
Limonene-carvacrol: A combination of monoterpenes with enhanced antileishmanial activity
FavorávelEstudo LaboratorialLeishmaniose
2021
Limonene, a citrus monoterpene, non-complexed and complexed with hydroxypropyl-β-cyclodextrin attenuates acute and chronic orofacial nociception in rodents: Evidence for involvement of the PKA and PKC pathway
FavorávelEstudo em AnimaisDor Dor — Crônica Dor — Aguda
2021
Linalool Alleviates A β 42-Induced Neurodegeneration via Suppressing ROS Production and Inflammation in Fly and Rat Models of Alzheimer's Disease
FavorávelEstudo em AnimaisInflamação Doenças Neurodegenerativas Doença de Alzheimer
2021
Linalool as a Therapeutic and Medicinal Tool in Depression Treatment: A Review
FavorávelMetanáliseDepressão
2021
Linalool attenuates acquisition and reinstatement and accelerates the extinction of nicotine-induced conditioned place preference in male mice
FavorávelEstudo em AnimaisDependência Química Dependência — Nicotina
2021
Linalool exhibits therapeutic and protective effects in a rat model of doxorubicin-induced kidney injury by modulating oxidative stress
FavorávelEstudo em AnimaisEstresse Oxidativo
2021
Linalool odor‐induced analgesia is triggered by TRPA1-independent pathway in mice
FavorávelEstudo em AnimaisDor Dor — Aguda
2021
Linalool reverses benzene-induced cytotoxicity, oxidative stress and lysosomal/mitochondrial damages in human lymphocytes
FavorávelEstudo LaboratorialEstresse Oxidativo
2021
Linking the Endocannabinoidome with Specific Metabolic Parameters in an Overweight and Insulin-Resistant Population: From Multivariate Exploratory Analysis to Univariate Analysis and Construction of Predictive Models
FavorávelEstudo LaboratorialInflamação Doenças Cardiovasculares (DCV)Obesidade Anandamida (AEA)Endocanabinoide (não especificado)+9
2021
Liposomal drug delivery of Corchorus olitorius leaf extract containing phytol using design of experiment (DoE): In-vitro anticancer and in-vivo anti-inflammatory studies
FavorávelEstudo em AnimaisCâncer Inflamação
2021
Localisation of Cannabinoid and Cannabinoid-Related Receptors in the Horse Ileum
InconclusivoEstudo LaboratorialAplicações Veterinárias
2021
Long-Acting Injectable Antipsychotic Treatment in Schizophrenia and Co-occurring Substance Use Disorders: A Systematic Review
FavorávelMetanáliseDependência Química Dependência — Cannabis Psicose+5
2021
Long-term cannabidiol treatment for seizures in patients with tuberous sclerosis complex: An open-label extension trial
FavorávelEnsaio ClínicoEpilepsia Epilepsia — Síndrome de Dravet Epilepsia — Lennox-Gastaut CBD Farmacêutico
2021
Long-Term Consequences of Adolescent Exposure to THC-Rich/CBD-Poor and CBD-Rich/THC-Poor Combinations: A Comparison with Pure THC Treatment in Female Rats
InconclusivoEstudo em AnimaisEfeitos Adversos da Cannabis
2021
Long-term safety and efficacy of add-on cannabidiol in patients with Lennox-Gastaut syndrome: Results of a long-term open-label extension trial
FavorávelEnsaio Clínico Duplo-CegoEpilepsia Epilepsia — Lennox-Gastaut CBD Farmacêutico
2021
Long-term safety and efficacy of highly purified cannabidiol for treatment refractory epilepsy
FavorávelEnsaio ClínicoEpilepsia CBD Farmacêutico
2021
Longitudinal course of mental health symptoms among veterans with and without cannabis use disorder
DesfavorávelEnsaio ClínicoDependência Química Efeitos Adversos da Cannabis Dependência — Cannabis+5
2021
Longitudinal impact of cannabidiol on EEG measures in subjects with treatment-resistant epilepsy
FavorávelEnsaio ClínicoEpilepsia CBD Farmacêutico
2021
Lower-Risk Cannabis Use Guidelines (LRCUG) for reducing health harms from non-medical cannabis use: A comprehensive evidence and recommendations update
FavorávelMetanáliseEfeitos Adversos da Cannabis
2021
LPS-mediated neutrophil VEGF-A release is modulated by cannabinoid receptor activation
FavorávelEstudo LaboratorialSepse
2021
Lung cancer patient who had declined conventional cancer treatment: could the self-administration of ‘CBD oil’ be contributing to the observed tumour regression?
FavorávelMetanáliseCâncer Câncer — Pulmão
2021
Management of Acute Lung Injury: Palmitoylethanolamide as a New Approach
FavorávelEstudo em AnimaisInflamação COVID-19 Estresse Palmitoiletanolamida (PEA)+1
2021
Marijuana liberalization policies and perinatal health
InconclusivoMetanáliseGestação
2021
Marijuana Use Among Adult Liver Transplant Candidates and Recipients
InconclusivoMetanáliseRejeição de Transplante
2021
Marijuana use and sleep quality during pregnancy
InconclusivoEnsaio ClínicoInsônia e Distúrbios do Sono Gestação
2021
Marijuana Use during Pregnancy and Preterm Birth: A Prospective Cohort Study
FavorávelMetanáliseGestação
2021
Marijuana-induced acute myocardial infarction in a young adult male
DesfavorávelMetanáliseDoenças Cardiovasculares (DCV)Infarto
2021
Marijuana-related Reversible Cerebral Vasoconstriction Syndrome
DesfavorávelMetanáliseAVC
2021
Marijuana, but not alcohol, use frequency associated with greater loneliness, psychological distress, and less flourishing among young adults
DesfavorávelMetanáliseAnsiedade Depressão
2021
Maternal and Fetal Pharmacokinetic Analysis of Cannabidiol during Pregnancy in Mice
InconclusivoEstudo em AnimaisGestação
2021
Maternal omega-3 intake differentially affects the endocannabinoid system in the progeny`s neocortex and hippocampus: Impact on synaptic markers
InconclusivoEstudo em AnimaisGestação Ômega-3
2021
Measuring the Change in Health-Related Quality of Life in Patients Using Marijuana for Pain Relief
FavorávelMetanáliseDor Dor — Crônica
2021
Mechanism deconvolution of Qing Fei Pai Du decoction for treatment of Coronavirus Disease 2019 (COVID-19) by label-free integrative pharmacology assays
FavorávelEstudo LaboratorialCOVID-19
2021
Mechanism of Action of Limonene in Tumor Cells: A Systematic Review and Meta-Analysis
FavorávelMetanáliseCâncer
2021
Mechanisms of cannabis impairment: Implications for modeling driving performance
InconclusivoMetanáliseEfeitos Adversos da Cannabis
2021
Mechanistic Evaluation of Linalool Effect against Renal Ischemia- Reperfusion Injury in Rats
FavorávelEstudo em AnimaisDoenças Cardiovasculares (DCV)Lesão de Reperfusão Doença Renal Crônica
2021
Mechanistic insights into Candida biofilm eradication potential of eucalyptol
FavorávelEstudo LaboratorialInfecções Fúngicas
2021
Medical cannabinoids for treatment of neuropsychiatric symptoms in dementia: a systematic review
FavorávelMetanáliseDisfunção Cognitiva Doenças Neurodegenerativas Insônia e Distúrbios do Sono THC Farmacêutico THC:CBD Farmacêutico+6
2021
Medical Cannabis as a Substitute for Prescription Agents: A Systematic Review and Meta-analysis
FavorávelMetanáliseDor Ansiedade Dor — Crônica+1
2021
Medical Cannabis Certification Is Associated With Decreased Opiate Use in Patients With Chronic Pain: A Retrospective Cohort Study in Delaware
FavorávelMetanáliseDor Dependência Química Dor — Crônica+1
2021
Medical Cannabis for Chronic Noncancer Pain: A Systematic Review of Health Care Recommendations
FavorávelMetanáliseDor Dor — Crônica HIV/AIDS
2021
Medical Cannabis for Headache Pain: a Primer for Clinicians
FavorávelMetanáliseDor Dor — Crônica Dependência — Opioides+1
2021
Medical cannabis for severe treatment resistant epilepsy in children: a case-series of 10 patients
FavorávelEnsaio ClínicoEpilepsia
2021
Medical cannabis for the treatment of fibromyalgia syndrome: a retrospective, open-label case series
FavorávelMetanáliseFibromialgia Tetraidrocanabinol (THC)
2021
Medical Cannabis in Oncology: a Valuable Unappreciated Remedy or an Undesirable Risk?
InconclusivoMetanáliseDor Câncer Ansiedade+6
2021
Medical cannabis or cannabinoids for chronic non-cancer and cancer related pain: a systematic review and meta-analysis of randomised clinical trials
InconclusivoMetanálise ClínicaDor Dor — Crônica Insônia e Distúrbios do Sono+1
2021
Medical cannabis treatment for chronic pain: Outcomes and prediction of response
FavorávelMetanáliseDor Dor — Crônica
2021
Medical Cannabis Use Among Older Adults in Canada: Self-Reported Data on Types and Amount Used, and Perceived Effects
FavorávelMetanáliseDor Câncer Ansiedade+6
2021
Medical Cannabis, Headaches, and Migraines: A Review of the Current Literature
FavorávelMetanáliseEnxaqueca
2021
Medication Overuse Headache in Chronic Migraine Patients Using Cannabis: A Case-Referent Study
DesfavorávelMetanáliseEnxaqueca
2021
Medicinal Applications of Cannabinoids Extracted from Cannabis sativa (L.): A New Route in the Fight Against COVID-19?
FavorávelMetanáliseDor Câncer Dor — Crônica+6
2021
Medicinal applications of cannabis/cannabinoids
InconclusivoMetanáliseDor Epilepsia Insônia e Distúrbios do Sono CBD Farmacêutico
2021
Mediterranean Diet and Neurodegenerative Diseases: The Neglected Role of Nutrition in the Modulation of the Endocannabinoid System
FavorávelMetanáliseInflamação Doenças Neurodegenerativas Dieta
2021
Mediterranean diet consumption affects the endocannabinoid system in overweight and obese subjects: possible links with gut microbiome, insulin resistance and inflammation
FavorávelEnsaio ClínicoInflamação Obesidade Diabetes Anandamida (AEA)2-Araquidonoilglicerol (2-AG)+3
2021
Medium-throughput zebrafish optogenetic platform identifies deficits in subsequent neural activity following brief early exposure to cannabidiol and Δ9-tetrahydrocannabinol
DesfavorávelEstudo em AnimaisAlterações Cerebrais Neonatais
2021
Metabolic Consequences of Gestational Cannabinoid Exposure
DesfavorávelMetanáliseDoenças Cardiovasculares (DCV)Obesidade Diabetes Anandamida (AEA)Endocanabinoide (não especificado)+4
2021
Metabolomic Profile and Antioxidant/Anti-Inflammatory Effects of Industrial Hemp Water Extract in Fibroblasts, Keratinocytes and Isolated Mouse Skin Specimens
FavorávelEstudo LaboratorialInflamação Estresse Oxidativo Ácido Canabidiólico (CBD-a)
2021
Micro Composite Palmitoylethanolamide/Rutin Reduces Vascular Injury through Modulation of the Nrf2/HO-1 and NF-kB Pathways
FavorávelEstudo LaboratorialInflamação Doenças Cardiovasculares (DCV)Estresse Oxidativo Palmitoiletanolamida (PEA)+1
2021
Micronized / ultramicronized palmitoylethanolamide (PEA) as natural neuroprotector against COVID-19 inflammation
FavorávelMetanáliseInflamação COVID-19 Palmitoiletanolamida (PEA)
2021
Minor Cannabinoids: Biosynthesis, Molecular Pharmacology and Potential Therapeutic Uses
FavorávelMetanáliseCanabigerol (CBG)Canabinol (CBN)+4
2021
Mixed methods study of the potential therapeutic benefits from medical cannabis for patients in Florida
FavorávelMetanáliseDor Dor — Crônica Depressão+7
2021
Moderator effects in a randomized controlled trial of the Common Elements Treatment Approach (CETA) for intimate partner violence and hazardous alcohol use in Zambia
FavorávelMetanáliseDependência Química Dependência — Cannabis Depressão+4
2021
Modification of the hemodynamic and molecular features of phosphine, a potent mitochondrial toxicant in the heart, by cannabidiol
FavorávelEstudo em AnimaisDoenças Cardiovasculares (DCV)Estresse Oxidativo Infarto
2021
Modulation of Noradrenergic and Serotonergic Systems by Cannabinoids: Electrophysiological, Neurochemical and Behavioral Evidence
FavorávelMetanáliseDor Ansiedade Dor — Crônica+2